Biology & bio-education - supported over (many, many) years by

His totally wonderful family
Spencer I. Browne
Pew Biomedical Trust
March of Dimes Birth Defects Foundation
  American Cancer Society
Muscular Dystrophy Association
American Heart Association
NSF / NIH

Linda Crnic Institute

 

WOW!


Recent publication (2010 to the present) ORCID  
*
Undergraduate authors & link to mad scientist answers: 138 and counting.
orcid-id
The late neolithic  | Those wonderful 80s
The wacky 90s  | The oughts

in the midst of pondering, thinking, experimenting & writing:

sphere

 

Klymkowsky, M.W. 2016 - 2018. PLoS Science-Education Blog Posts

– Bilge Birsoy & an array of birlliantundergraduate. dCas9 repression of Slug/Rtn3 expression
+ BioID proximity tagging of Chibby's neighbors
+ interaction network mapping in Xenopus .

Development of progressive assessments in molecular biology.


Cooper, M.M. & M.W. Klymkowsky. 2015-8. Chemistry, Life, the Universe & Everything, available free on-line twits   Klymkowsky, M.W. & M.M. Cooper. 2015-8.
Biofundamentals available free on-line

Submitted, accepted or published note: only peer reviewed papers are numbered).

114. McClure-Begley, T.D., C.C. Ebmeier, K.E. Ball, Z. Poss, I. Kogut, G.C. Bilousova, M.W.Klymkowsky & W.M. Old 2018. Cerebral organoid proteomics reveals signatures of dysregulated forebrain development associated with human trisomy 21.bioRxiv

Klymkowsky, M.W. 2018. Constrain Speculation to Protect the Integrity of Science. What we can know about biology before the last universal common ancestor is limited—and we should be circumspect in filling in the gaps. The Scientist on-line 18 June 2018

113. Klymkowsky, M.W. 2018. Whole-mount Immunocytochemical Methods in Xenopus. Xenopus CSHL Protocols, S. Moody, ed. in press
(images of vimentin →)

112. McClure-Begley, T.D. & M.W. Klymkowsky. 2017. Nuclear roles for cilia-associated proteins. Cilia. 6:8

vimentin in xenopus

111. Lai, M.B, C. Zhang, J. Shi, V. Johnson, L. Khandan, J. McVey, M.W. Klymkowsky, Z. Chen & H.J. Junge. 2017. TSPAN12 is a Norrin Co-Receptor that Amplifies Frizzled4 Ligand Selectivity and Signaling. 19:2809-2822.

110. Champagne Queloz, A., M.W. Klymkowsky, E. Stern, Ernst Hafen & K. Köhler. 2017. Diagnostic of students' misconceptions using the Biological Concepts Instrument: A method for conducting an educational needs assessment, PLoS One,

3body 109. Klymkowsky, M.W., J. Rentsch, E. Begovic & M.M. Cooper. 2016. The design and transformation of Biofundamentals: a non-survey introductory evolutionary and molecular biology course. LSE winter;15. pii: ar70.

108. Champagne-Queloz, A. M.W. Klymkowsky, E. Stern, E. Hafen & K. Kohler. 2016. Debunking Key and Lock Biology: Exploring the prevalence and persistence of students’ misconceptions on the nature and flexibility of molecular interactions. Science Matters, link.

– Klymkowsky, M.W., K. Kohler, & M.M. Cooper. 2016. Diagnostic assessments of student thinking about stochastic processes. on bioArXiv.


107. Zhao, Y., J. Shi, M. Winey & M.W. Klymkowsky. 2016. Identifying domains of EFHC1 involved in axonemal localization, ciliogenesis, and the regulation of Wnt signaling. Dev. Biol. 411: 257-65.

Cooper, M.M. & M.W. Klymkowsky. 2016. Chemistry, Life, the Universe & Everything: An Evidence-Based, Transformed General Chemistry Curriculum. AAAS/NSF Symposium on Envisioning the Future of Undergraduate STEM Education.

– Klymkowsky, M.W., S.P. Bryfczynski & M.M. Cooper. 2016 Bringing useful insights into student thinking to course design, delivery, and evaluation using the beSocratic formative assessment system. AAAS/NSF Symposium on Envisioning the Future of Undergraduate STEM Education.

  efhc1 xenopus

106. Square, T., M. Romášek, M. Cattell, D. Jandzik, M.W. Klymkowsky & D.M. Medioros. 2015. CRISPR/Cas9-mediated mutagenesis in the sea lamprey, Petromyzon marinus: a powerful tool for understanding ancestral gene functions in vertebrates. Development, 142: 4180-4187.

105. Williams, J.C., S.M. Underwood, M.W. Klymkowsky & M.M. Cooper. 2015. Are non-convalent interactions an Achilles heel in chemistry instruction and student understanding. J. Chem. Ed., 92:1979–1987.

– McClure-Begley, T.D., C.E. Ebmeier, K.E. Ball, M.W. Klymkowsky, and W.M. Old. 2015. Proteome-wide effects of Down Syndrome explored with human induced pluripotent stem cell derived cerebral organoids. Society for Neuroscience abstract (press release).

notochords

 

– Bryfczynski, S., Pargas, R.P., Cooper, M.M., Klymkowsky, M.W,, Hester, J., & N.P. Grove. 2015. Classroom uses for beSocratic. in The Impact of Pen and Touch Technology on Education. Hammond, T., Valentine, S., Adler, A., & Payton, M. (Eds.) Springer.

104. Shi, J., Y. Zhou, T. Vonderfecht, M. Winey & M.W. Klymkowsky. 2015. Centrin-2 mediated regulation of FGF/FGFR gene expression in Xenopus. Scientific Reports, 5:10283. doi: 10.1038/srep10283.

103. Shi, J., Y, Zhao, D. Galati, M. Winey & M.W. Klymkowsky. 2014. Chibby functions in Xenopus ciliary assembly, embryonic development, and the regulation of gene expression. Developmental Biology, 395: 287–298.

– Klymkowsky, M.W. 2014. Physics for (molecular) biology students. invited essay for American Physical Society's Forum on Education newsletter. Fall issue.

– Cooper, M.M., S. Underwood, S. Bryfczynski & M.W. Klymkowsky. 2014. A Short History of the Use of Technology to Model and Analyze Student Data for Teaching and Research. in Tools of Chemistry Education Research, 1166.

 

102. Redish, E.F., C. Bauer, K.L. Carleton, T.J. Cooke, M.M. Cooper, C.H. Crouch, B.W. Dreyfus, B. Geller, J. Giannini, J. Svoboda Gouvea, M.W. Klymkowsky, W. Losert, K. Moore, J. Presson, V. Sawtelle, K. V. Thompson, C. Turpen, R.K.P. Zia. 2014. NEXUS/Physics: An interdisciplinary repurposing of physics for biologists. Am. J. Phys 82: 368

101. Cooper, M.M., M.W. Klymkowsky & N.M. Becker. 2014. Energy in Chemical Systems: An integrated approach. in R.F. Chen et al. (eds.), Teaching and Learning of Energy in K-12 Education,DOI 10.1007/978-3-319-05017-1__17 Springer Verlag.

–Garvin-Doxas, K., M.W. Klymkowsky, I. Doxas, & W. Kintsch. 2014. Using technology to accelerate the construction of concept inventories: Latent Semantic Analysis and the Biology Concept Inventory. 6th International Conference on Computer Supported Education, CSEDU, Barcelona.

  cby centrin head

– Redish, E., Bauer, C., Carleton, K., Cooke,T., Cooper M.M., Crouch C., Dreyfus, B., Geller, B., Giannini, J., Svoboda Gouvea, J., Klymkowsky, M.W., Losert, W., Moore, K., Presson, J., Sawtelle, V., Thompson, K., Turpen, C., 2013. NEXUS/Physics: Rethinking physics for biology and pre-med students. AAAS Vision and Change meeting poster, August 2013.

100. Repenning, A., A. Basawapatna, & M.Klymkowsky. 2013. Making educational games that work in the classroom, International Games Innovation Conference 2013. IEEE Games Innovation conference (IGIC).

Bryfcyzinski, S., R.P. Pargas, M.M. Cooper, M. Klymkowsky, J. Hester, N.P. Grove. 2013. Classroom uses for beSocratic. Conference abstract.

Bryfcyzinski, S., B.C. Dean, R.O. Pargas, M.M. Cooper & M.W. Klymkowsky. 2013. Teaching data structures with beSocratic. ACM abstract. http://dl.acm.org/citation.cfm?doid=2445196.2445429.

99. Cooper, M.M. & M.W. Klymkowsky. 2013. Chemistry, Life, the Universe and Everything: a new approach to general chemisry and a model for curriculum reform, J.Chem. Educ., 90: 1116–1122 (and the cover!)

98. Cooper, M.M. & M.W. Klymkowsky. 2013. The trouble with chemical energy: why understanding bond energies requires an interdisciplinary systems approach. CBE Life Sci. Education,12:306-12. doi: 10.1187/cbe.12-10-0170.

97. Klymkowsky, M.W. & M.M. Cooper. 2012. Now for the hard part: the path to coherent curricular design. BAMBED, 40: 271-272. (PMID: 22807431)

96. Cooper, M.M, S.M. Underwood, C. Hilley & M.W Klymkowsky. 2012. Development and assessment of a molecular structure and properties learning progression. J. Chem. Educ., 89: 1351–1357.

95. Bryfcyzinski, S., R.O. Pargas, M.M. Cooper & M.W. Klymkowsky. 2012. Analyzing and visualizing student work with BeSocratic. ACM-SE '12 Proceedings of the 50th Annual Southeast Regional Conference. P: 349-350 (doi: 10.1145/2184512.2184599)

 

clue cover

94. Henson, K., M.M. Cooper, & M.W. Klymkowsky. 2012. Turning randomness into meaning at the molecular level using Muller’s morphs. Biology Open 1:405-10. (PMID: 23213431)

93. Cattell, M., A. Garnett, M.W. Klymkowsky & D.M.Medioros. 2012. A maternally established soxB1/soxF axis is a conserved feature of chordate germ layer. Evo. & Devo., 14:104-115.

92. Shi, J., H. Zheng, R.D. Dowell & M.W. Klymkowsky. 2012. sizzled function and secreted network interactions in the dorsolateral mesoderm. Biol. Open., 1: 286-294 (PMID: 23213419)

91. Trujillo, C*. M.M. Cooper & M.W. Klymkowsky. 2012. Using graph-based assessments within Socratic tutorials to reveal and refine students’ analytical thinking about molecular networks. BAMBED 40:100-107. doi: 10.1002/bmb.20585

90. Klymkowsky, M.W. 2011. Mitochondrial activity, embryogenesis, and the dialogue between the big and little brains of the cell. Mitochondrion, 11:814-819.

89. Shi, J., C. Severson, J. Yang, D. Wedlich & M.W. Klymkowsky. 2011. Snail2-specific, BMP- and Wnt- dependent mesodermal induction of neural crest. Development 138: 3135-45.

– Klymkowsky, M.W. 2011c. Teaching disconcerting scientific ideas. ASBMB Today, June

– Klymkowsky, M.W. 2011b. Why is understanding evolution hard? ASBMB Today, March.

– Klymkowsky, M.W. 2011a. Getting serious about science education. ASBMB Today, February.

88. Shi, J., J. Power & M.W. Klymkowsky. 2011. Revealing student thinking about experimental design and control experiments. Int. J. Sci. Ed. 5:1-16.

– Klymkowsky. M.W. 2011. Review of "Why evolution works (and creationism fails). by M. Young & P.K. Strode.  Reports of the National Center for Science Education.

– Klymkowsky, M.W., S. Underwood, & R.K. Garvin-Doxas. 2010. The Biological Concepts Instrument (BCI), a diagnostic tool to reveal student thinking. arXiv:1012.4501v1.

87. Klymkowsky, M.W., C. Cortez-Rossi, & K.B. Artinger. 2010 Mechanisms driving neural crest induction and migration in the zebrafish and Xenopus laevis. Cell Adhesion & Migration, 4: 595-608.

86. Hikasa, H.. J. Ezan, X. Li, M.W. Klymkowsky & S. Sokol. 2010. Wnt-dependent phosphorylation of TCF3 leads to transcriptional derepression during vertebrate anteroposterior axis specification. Dev. Cell, 9:521-32.

85. Klymkowsky, M.W. 2010. Thinking about the conceptual foundations of the biological sciences. CBE Life Science Educ. 9: 405-7.

84. Cooper, M.M., N. Grove, S. Underwood & M.W. Klymkowsky. 2010 Lost in Lewis Structures: an investigation of student difficulties in developing representational competence. J. Chem Ed.,DOI: 10.1021/ed900004y.