Sizzled
Secreted Wnt and BMP1/Xlr inhibitor
Salic et al 1997.Sizzled: a secreted Xwnt8 antagonist expressed in the ventral marginal zone of Xenopus embryos.
Development. 124:4739-48.
Lee et al. 2006.Embryonic dorsal-ventral signaling: secreted frizzled-related proteins as inhibitors of tolloid proteinases.
Cell. 124:147-59.
plasmid source: Eddy DeRobertis
relevant information for making probe, i.e. restriction
sites, promoter
typical staining pattern
(jpeg 150 dpi, 60% compression
useful description including stage: ventral/neural crest/placodes
picture source: Courtney Severson |